Module Notes

Bioreactor Analysis and Design

This module will not be offered for this semester

Faculty Member (Members)

PD407

Undergraduate

Fall

5th Year

9th Semester (5th Year, Fall)

Module Type

Core Chemical Engineering

Module Category

Thematic Unit Electives, Group A

Course Code:

CHM_E_A3

Course URL:

E-Class (CMNG2192)

Credits:

ECTS Credits:

Module Availability on Erasmus Students:

Teaching Language:

Greek

Laboratory:

Lectures:

3h/W

Τutorial:

Project/Homework:

10/Semester

Teaching Type

Student's office hours:

Module Details

Learning Outcomes

Application of knowledge of basic biology, reaction engineering and biokinetics in designing and analyzing systems of bioreactors.

Application of mathematical and computational methods of analyzing and solving systems of differential equations representing mathematical models of bioreactors.

Constuction and computational analysis of mathematical models of systems of bioreactors.

Prerequisites

Knowledge of basic biology, principles of bioengineering, reaction engineering, mathematical and computational methods of analyzing and solving systems of differential equations.

Module content

BIOREACTORS. Chemostat, Monod’s model in the chemostat. Product formation. Maintenance and endogenous metabolism. Non-ideal bioreactors. Cell attachment to chemostat walls.

DYNAMIC BEHAVIOR OF BIOREACTORS. Elements of system dynamics. Dynamic behavior of the chemostat. Monod’s model. Andrews’s model.

LIMITATION OF THE MICROBIAL GROWTH RATE FROM MULTIPLE NUTRIENTS. Classification of pairs of nutrients. Complementary nutrients. Substitutable nutrients. Generalized models of microbial growth.

DISTRIBUTED MODELS. Population balance of particles. Breakage process. Aggregation process. Balance of environmental components. Cell population balance in a chemostat.

MIXED CULTURES OF MICROORGANISMS. Classification of microbial interactions. Direct microbial interactions. Indirect microbial interactions. Combinations of interactions.